Job Requisition Number: 27466. Tuberculosis has been a major global health concern for well over a century. Although many potential treatments have been vigorously pursued, conventional strategies have failed to eradicate TB infection and, in fact, the global threat has grown over the last couple decades, potentially stemming from the fact that treatment attempts have neglected to take into account the deeply integrated, symbiotic-like relationship between Mycobacterium tuberculosis and its host that has developed over 40,000 years of human/bacterial co-evolution.
The Cox Lab (housed in the UC Berkeley MCB Department) aims to understand the key mechanisms that dictate the M. tuberculosis-human relationship with the goal of breaking these ties, targeting either host or pathogen factors to eliminate M. tuberculosis infection and use that knowledge to contribute to solving a steadily increasing threat in global health.
For more information, visit http://www.coxlab.berkeley.edu/
•Assist and perform research experiments using Molecular/cell biology and computational approaches: DNA cloning, qPCR, transfection, lentivirus production, CRISPR genetics, next-generation sequencing, genomics, transcriptomics. •Learn and carry out biochemical techniques such as SDS-PAGE, affinity purification, western blotting. •Assist and carry out molecular genetic methods to overexpress and silence gene expression in mammalian cell culture, molecular cloning techniques and mutagenesis, cell biological assays to assess protein function and localization, western blotting, quantitative PCR analysis, and other assays that are critical for advancing our studies of infectious diseases. •Present in lab meetings of research accomplishments, and participate in manuscript and grant writing. •Supervising undergraduate student assistants to ensure successful completion of fundamental tasks, including ordering/stocking laboratory supplies, preparation of lab stocks, mouse breeding, and general laboratory maintenance. •Assist with on-boarding of new lab personnel, including key car access and safety training •Coordinating vendors in procurement and maintenance of lab equipment •Perform other duties as assigned•Demonstrated experience with molecular cloning and culturing of bacteria and/or mammalian cells •Facility with computer programming and/or working with large data sets •Familiarity with DNA software •Ability to independently make solutions based on molarity and % composition
The University of California was chartered in 1868 and its flagship campus - envisioned as a "City of Learning" - was established at Berkeley, on San Francisco Bay. Today the world's premier public university and a wellspring of innovation, UC Berkeley occupies a 1,232 acre campus with a sylvan 178-acre central core. From this home its academic community makes key contributions to the economic and social well-being of the Bay Area, California, and the nation.