The assistant/associate/full specialist in this position is expected to conduct IND (investigational new drug)-enabling studies for our clinical trial of cancer immunotherapy for patients with glioma. Hence, the studies to be conducted include: 1) designing and cloning of novel lentiviral chimeric antigen receptor (CAR) vector; 2) transduction of human T lymphocytes with lentiviral CAR; 3) evaluation of anti-glioma immune responses by the CAR-transduced T lymphocytes using a variety of immunological assays, such as cytotoxicity assays, cytokine release assays and flow-cytometry; and 3) in vivo studies using immunodeficient mice bearing human glioma xenografts and infusion of CAR-transduced T lymphocytes.
Sufficient expertise and knowledge in relevant systems; i.e. DNA cloning, culture of T lymphocytes, immunological assays and handling of mouse models is required. Post-graduate training in field is desirable. Specialists appointed at the Assistant or Associate rank must possess at minimum a master’s degree (or equivalent degree) or must have at least five years of research experience. Specialists appointed at the full rank must possess a terminal degree (or equivalent degree) or must have at least ten or more years of research experience. Applicant’s materials must list (pending) qualifications upon submission. Applicants must have obtained the degree requirement for the Specialist rank by the time of hire.
Screening of applicants will begin immediately and will continue as needed throughout the recruitment period. Salary and rank will be commensurate with the applicants experience and training. Please apply online at https://aprecruit.ucsf.edu/JPF03077.
UC San Francisco seeks candidates whose experience, teaching, research, or community service that has prepared them to contribute to our commitment to diversity and excellence. The University of California is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion,
Internal Number: JPF03077
About University of California, San Francisco
The University of California, San Francisco (UCSF) is a leading university dedicated to promoting health worldwide through advanced biomedical research, graduate-level education in the life sciences and health professions, and high-quality patient care. It is the only UC campus in the 10-campus system dedicated exclusively to the health sciences.