Research - Laboratory/Non-Laboratory, Staff/Administrative
Responsibilities 35%--Carry out research investigations aimed at understanding placental development using cell culture and translational models. Duties include:
1) Performing cell culture work including maintenance of cell lines obtained from human placenta, generation of stably transduced cell lines, analysis of cell lines by quantitative PCR, western blotting, microscopy, metabolomics and other techniques as indicated. 2) Isolating and maintaining trophoblasts from human placenta 3) Maintaining accurate records and carefully preparing, collecting and organizing cell lines, samples and specimens 4) Submit and maintain protocols necessary for completion of work including those to the Institutional Review Board 5) Promote lab safety including keeping safety records for personnel, managing lab inspections, maintaining safety procedures in lab, and training all employees on lab safety measures and additional protocols as needed.
45% --Carry out investigations aimed at understanding impact of placental development on fetal outcomes using rodent models. This will require:
1) Regularly assessing rodent status 2) Providing interventions to rodents 3) Harvesting rodent specimens 4) Maintaining rodent colony including breeding, weaning, genotyping and sacrificing 5) Maintaining Institutional Animal Care and Use protocols and participating in training as needed
10% --Support overall laboratory efforts by:
1) Assisting other members of laboratory with research studies, experiments and assays including acquisition of data and preparation of samples as needed. 2) Ordering reagents and supplies. 3) Maintaining necessary shared resources and reagents to support a well-functioning lab--this will include dishwashing, autoclaving and regular assessment of resources.
10% --Participate in intellectual aspects of project by:
1) Participating in experimental design 2) Analyzing data accurately and preparing and presenting findings in meetings 3) Reviewing literature and summarizing findings 4) Reviewing funding applications and papers for submission.
***All required qualifications must be documented in application materials***
-BA or BS in biological science, biochemistry, physiology, chemistry plus one year of related experience or combination or education and experience to equal five years -Experience with cell culture and knowledge of molecular biology techniques -Experience with rodent husbandry including weaning, genotyping and colony management -Experience maintaining accurate documentation in laboratory records and experience with computer software including Microsoft products and NCBI web-based available resources (Pubmed) -Willingness to learn new techniques and work with rodent and human tissue samples - Excellent communication, interpersonal and organizational skills. - Demonstrated ability to work independently, as well as with others - Ability to design and carry out experiments. - Ability to train additional research team members on experimental techniques and standard protocols. -Must be physically able to wear protective equipment and work with laboratory mice without restriction. Additionally, must be able to provide standard care to research animals and complete required research protocols. -Must be willing to work with biospecimens and cell lines collected from human subjects, and successfully complete all compliance training. -Flexibility to work outside standard scheduled hours occasionally is required to accommodate research.
Preferred Qualifications - Ability to participate in experimental design, collect and analyze data. - Ability to participate in drafting proposals and writing manuscripts. - Demonstrated experience managing scientific projects in the past. - Demonstrated teaching or leadership experience in the past.
Internal Number: 337838
About University of Minnesota, Twin Cities
The University of Minnesota, founded in the belief that all people are enriched by understanding, is dedicated to the advancement of learning and the search for truth; to the sharing of this knowledge through education for a diverse community; and to the application of this knowledge to benefit the people of the state, the nation, and the world.