Research - Laboratory/Non-Laboratory, Staff/Administrative
This position would support Basic and Translational Pain Research within the Department of Anesthesiology and Critical Care Medicine (ACCM). Within the Pain Research Group (Sivanesan Neuromodulation and Pharmacologic and Electrical Translational (PET) Pain Neuromodulation Research Labs). Applicants should have experience working with animals in research environment. Position assists with the technical aspects of laboratory studies and experiments including documentation and preparation of materials, performing physiological studies on animals, animal surgery related to developing models of peripheral neuropathic pain (including chemotherapy-induced peripheral neuropathy), cancer pain, and other conditions, behavioral assays, cell culture, administering agents and conducting molecular work designed to pain research.
Specific Duties & Responsibilities
Under the general supervision of a faculty investigator or laboratory supervisor, he/she will perform laboratory tasks and complete routine assays following common or established protocols and procedures. He/she will be trained prior to work with supervision and guidance from the principal investigators of the group. Keep accurate, detailed laboratory records. Additional responsibilities will be to aid the principal investigator in the writing of progress reports; maintain and update procedures; protocols and approvals for work with laboratory material; prepare presentations and summaries of experiments; aid in the preparation of manuscripts and grant submissions. Independent troubleshooting of technical and experimental issues. Exercises professional and scientific judgment and assumes responsibility for decisions, consequences, and results. Engages in regular and continuous decision making having an impact on the success of the laboratory.
Techniques of interest include, but are not limited to, basic animal surgery technique in rodents (e.g., xenograft implantation, nerve ligation, catheter implantation), behavioral pharmacology (drug delivery), animal behavioral testing techniques related to pain, addiction and anxiety, cell culture (mammalian), molecular and functional imaging, protein extraction/isolation, ELISA, western blot, real-time PCR, and immunocytochemistry. A basic understanding of theory behind the experiments is needed. Work requires applying basic analytical skills to implement assigned projects, and to identify and trouble-shoot situations needing special attention. Following approved experimental protocols, health records need to be maintained in accordance with AALAC guidelines.
Uses various software applications, such as spreadsheets, relational databases, electronic mail, World Wide Web, statistical packages, and graphics packages to assemble, manipulate and/or format data and/or test reports. Work can involve use of image analysis software to analyze images of tissue sections.
Monitors inventory levels, orders materials and supplies in accordance with established policies and procedures. Interacts with vendors and obtains quotes. Helps maintain lab equipment. Keeps laboratory and surgical recovery areas clean and orderly.
Bachelor's degree in biology, molecular biology, neuroscience, chemistry, or related field plus two (2) years of laboratory experience performing relevant techniques. Master's degree, with related graduate research, may substitute for experience to the extent permitted by the JHU equivalency formula.
* JHU Equivalency Formula: 30 undergraduate degree credits (semester hours) or 18 graduate degree credits may substitute for one year of experience. Additional related experience may substitute for the required education on the same basis. For jobs where equivalency is permitted, up to two years of non-related college course work may be applied towards the total minimum education/experience required for the respective job. *
Experience in working with experimental animal models. Master's degree in biology, molecular biology, neuroscience, chemistry, or related field; 2-4 years of laboratory experience.
Special Knowledge, Skills, and Abilities
Experience with mammalian tissue culture. Documented ability to work independently, but also collaboration with individuals from other research groups is required.
Physical requirements for the job:
No allergy to live animals (rodent). Sitting in normal seated position and standing for extended periods of time. Ability to use a keyboard and move about. Ability to see and hear within normal parameters.
Budget authority (indicate dollar amount of budget managed and type/level of authority):
R01, foundation, and intramural
Classified Title: Research Specialist II Working Title: Research Specialist II Role/Level/Range: ACRP/03/MB Starting Salary Range: $38,920 - $53,520 / Commensurate with experience Employee group: Full Time Schedule: Monday-Friday, Hours Vary, Up to 37.5 hrs/ week Exempt Status: Exempt Location: 04-MD:School of Medicine Campus Department name: 10002731-SOM Ane Pain Personnel area: School of Medicine
The successful candidate(s) for this position will be subject to a pre-employment background check.
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During the Influenza ("the flu") season, as a condition of employment, The Johns Hopkins Institutions require all employees who provide ongoing services to patients or work in patient care or clinical care areas to have an annual influenza vaccination or possess an approved medical or religious exception. Failure to meet this requirement may result in termination of employment.
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