Lawrence Berkeley National Lab's (LBNL),Biological Systems and Engineering Division has an opening for a Postdoctoral Scholar to join the Quantum Imaging project funded by Laboratory Directed Research and Development (LDRD) Program, located at the Advanced Biofuels and Bioproducts Process Development Unit (ABPDU) in Emeryville, CA.
Recent advances in 'quantum assisted sensing' have opened exciting new avenues for studying chemical and biological processes with optical resolution and a research collaboration at LBNL is integrating quantum sensing approaches into cell culturing and microfluidic systems. In this exciting role the Postdoc will design experiments to quantify cell-to-cell heterogeneity in bioreactors, seeking to obtain time-dependent non-invasive identification, quantification and localization of metabolite intermediates and products in genetically modified microbial species. This work will address fundamental questions in metabolic network rewiring, develop and apply unique chemical imaging methods and ultimately enable more robust biomanufacturing through better sensing.
What You Will Do:
Develop experimental platform to monitor key metabolic processes in living bacterial or yeast cells using a quantum sensing instrument in collaborator laboratories at LBNL
Acquire and analyze optical imaging and spectroscopic data, including 13C nuclear magnetic resonance data, from microbial populations and single cells
Collaborate with groups and user facilities at LBNL to design and perform quantum sensing experiments and complementary imaging and chemical analysis
Strategize and write grants to obtain additional funding on the topic of sensing microbial heterogeneity occurring during bioreactor cultivation
Draft manuscripts describing experimental work
Present results and discuss plans with funders
What is Required:
PhD degree in the field of microbiology, biochemistry, or similar field
Previous record of publications in peer-reviewed journals
Experience in analyzing and interpreting -omic data with strong quantitative/computational skills
Previous experience or interest in employing imaging tools as a method to observe phenotypic changes, such as with fluorescence microscopy, confocal microscopy, or cryoEM techniques to help resolve subcellular localization
Interest in developing quantum imaging tools for biological systems
Excellent written and verbal communication skills
Interest in mentoring and developing others
Familiarity with microbial imaging techniques
Detail oriented and highly organized
Self-motivated, able to work independently and organize own workload
Ability to interact professionally and productively with other members of the team
Previous experience or interest in spectroscopic characterization of biomolecules
Experience in prokaryotic protein localization analysis
This is a full-time1-year, postdoctoral appointment with the possibility of renewal based upon satisfactory job performance, continuing availability of funds and ongoing operational needs. You must have less than 4 years of paid postdoctoral experience. Salary for Postdoctoral positions depends on years of experience post-degree.
This position is represented by a union for collective bargaining purposes.
Salary will be predetermined based on postdoctoral step rates.
This position may be subject to a background check. Any convictions will be evaluated to determine if they directly relate to the responsibilities and requirements of the position. Having a conviction history will not automatically disqualify an applicant from being considered for employment.
Vision: To lead efforts that combine the power of biology with the tools of engineering to develop sustainable energy and biomanufacturing solutions and improve human health.
Mission:Advance a mechanistic and predictive understanding of complex biological systems over multiple scales in terms of their responses to manipulation, stress, disease and environmental challenges and translate this knowledge using engineering principles to develop resilient systems, tools, and processes for the efficient production of fuels, chemicals, materials, tissues, and therapeutics.
Berkeley Lab (LBNL) addresses the world's most urgent scientific challenges by advancing sustainable energy, protecting human health, creating new materials, and revealing the origin and fate of the universe. Founded in 1931, Berkeley Lab's scientific expertise has been recognized with 13 Nobel prizes. The University of California manages Berkeley Lab for the U.S. Department of Energy's Office of Science.
Working at Berkeley Lab has many rewards including a competitive compensation program, excellent health and welfare programs, a retirement program that is second to none, and outstanding development opportunities. To view information about the many rewards that are offered at Berkeley Lab- Click Here.
Equal Employment Opportunity: Berkeley Lab is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age, or protected veteran status. Berkeley Lab is in compliance with the Pay Transparency Nondiscrimination Provision under 41 CFR 60-1.4. Click here to view the poster and supplement: "Equal Employment Opportunity is the Law.
Lawrence Berkeley National Laboratory encourages applications from women, minorities, veterans, and other underrepresented groups presently considering scientific research careers.
Internal Number: 91384
About Lawrence Berkeley National Laboratory
In the world of science, Lawrence Berkeley National Laboratory (Berkeley Lab) is synonymous with excellence. Thirteen scientists associated with Berkeley Lab have won the Nobel Prize. Fifty-seven Lab scientists are members of the National Academy of Sciences (NAS), one of the highest honors for a scientist in the United States. Thirteen of our scientists have won the National Medal of Science, our nation's highest award for lifetime achievement in fields of scientific research. Eighteen of our engineers have been elected to the National Academy of Engineering, and three of our scientists have been elected into the Institute of Medicine. In addition, Berkeley Lab has trained thousands of university science and engineering students who are advancing technological innovations across the nation and around the world. Berkeley Lab is a member of the national laboratory system supported by the U.S. Department of Energy through its Office of Science. It is managed by the University of California (UC) and is charged with conducting unclassified research across a wide range of scientific disciplines. Located on a 200-acre site in the hills above the UC Berkeley campus that offers spectacular... views of the San Francisco Bay, Berkeley Lab employs approximately 4,200 scientists, engineers, support staff and students. Its budget for 2011 is $735 million, with an additional $101 million in funding from the American Recovery and Reinvestment Act, for a total of $836 million. A recent study estimates the Laboratory's overall economic impact through direct, indirect and induced spending on the nine counties that make up the San Francisco Bay Area to be nearly $700 million annually. The Lab was also responsible for creating 5,600 jobs locally and 12,000 nationally. The overall economic impact on the national economy is estimated at $1.6 billion a year. Technologies developed at Berkeley Lab have generated billions of dollars in revenues, and thousands of jobs. Savings as a result of Berkeley Lab developments in lighting and windows, and other energy-efficient technologies, have also been in the billions of dollars. Berkeley Lab was founded in 1931 by Ernest Orlando Lawrence, a UC Berkeley physicist who won the 1939 Nobel Prize in physics for his invention of the cyclotron, a circular particle accelerator that opened the door to high-energy physics. It was Lawrence's belief that scientific research is best done through teams of individuals with different fields of expertise, working together. His teamwork concept is a Berkeley Lab legacy that continues today.