Postdoctoral Scholar University of California Los Angeles
Requisition Number: JPF06200
Seeking excellent applicant with strong research track-record for a competitive post-doctoral fellowship in functional genomics of neurodegenerative disease in the Rexach Lab in the UCLA department of Neurology and Human Genetics. The Rexach group uses integrative multiomics analysis, including single nuclear ATAC and RNA sequencing, to identify cell-specific and multicellular molecular drivers of neurodegenerative dementias, and study their function in disease model systems, including human iPSC-derived spheroids. This fellow would lead a new single-cell and integrative bioinformatics study to identify both disorder-specific and disorder-convergent drivers and mechanisms of neurodegeneration, involving glial cells, and complete functional validation using stem cell-derived models. The goal of this work is to identify and validate new therapeutic targets for neurodegenerative dementias, including Alzheimer's disease and related disorders, none of which have effective cures or treatments.
Job Duties Bioinformatics analyses of single nuclear RNA and ATAC sequencing data, multi-omics integration, network-based driver analysis, and genomic analyses. Preparation of high-quality manuscripts to report research findings. Presentation at national and international meetings. Full participation in research group meetings and activities. Participation in training junior students and colleagues within the Rexach lab. Excellent coordination and communication with collaborators. Data management, accountability, and post-publication code and data sharing.
Skills, Knowledge, and Abilities needed for the position Ability to utilize bioinformatics codes and resources in R is required. Ability to code in R and/or Python are preferred. Experience in basic statistics in required. Experience in advanced statistics for big data research is preferred. Experience in transcriptomics, genomics, proteomics, or related analyses, are preferred. Experience in designing, executing and publishing scientific research is required. Experience in writing first-author scientific manuscripts is required. Strong desire to learn, innovate, discover and collaborate are required. Respect for all colleagues and community is expected and required.
The University of California is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age or protected veteran status. For the complete University of California nondiscrimination and affirmative action policy, see: UC Nondiscrimination & Affirmative Action Policy, https://policy.ucop.edu/doc/4000376/DiscHarassAffirmAction
UCLA is known worldwide for the breadth and quality of its academic, research, health care, cultural, continuing education and athletic programs. UCLA offers undergraduate degrees in more than 127 majors and graduate degrees in 198 program areas. UCLA has 11 highly regarded professional schools. Eight are ranked among the nation's top 15 in their field by U.S. News & World Report. UCLA is consistently among the most popular campus in the nation for undergraduate applicants. The University of California is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to age, race, color, religion, sex, national origin, disability, or protected veteran status. Benefits:UCLA offers a comprehensive benefits package, including an average of three weeks' vacation per year; an average of 12 days per year sick leave; 13 paid holidays per year; health, dental and optical benefits; life insurance; disability insurance; the University of California Retirement Plan with 5 year vesting and various voluntary UC Savings Plans. There are also special programs and privileges available, such as accessibility to cultural and recreational programs, athletic events, and the University Credit Union.