Overview CMAP is a Center of Excellence in Genome Science. Our Center is developing highly generalizable, reproducible and scalable technologies to generate and assess the functional impact of variants in human genes. Our goal is to facilitate variant interpretation to enable genome-guided precision medicine in clinical decision making.
Position Description The Center for the Multiplex Assessment of Phenotype (CMAP) is accepting applications for two full-time "CMAP Postdoctoral Scholar" positions starting in 2020.
Linking phenotype to genotype is one of the most pressing problems in biology. We are looking for near or recent grads to work on high-risk, high-reward methods development projects that will drive the mutational scanning field forward. This is a unique opportunity to work at the cutting edge of genomics and proteomics with a team of creative and talented scientists.
This position is designed to prepare trainees for research careers in acquiring and interpreting genomic data for use in biomedical research.
Compensation Competitive, plus generous benefits.
Available Projects/ Technologies Potential projects include computational and molecular methods development involving:
● Next generation sequencing
● Deep mutational scanning (DMS)
● Massively parallel reporter assays (MPRA)
● Generation of allelic series
● Genome editing and engineering
● Microscope-Assisted Visuospatial Sorting
● Proteomic approaches
● Variant effect prediction algorithms
● Repeat sequence genotyping
● Post-translational modification analysis
● Saturation Genome Editing (SGE)
● Variant library creation
● Cell differentiation assays
● Single cell – single variant transcriptomics
● Variant proteomics
Working environment The successful applicant will join one of the CMAP labs.
● Excellent organization, writing, presentation and communication skills
● Strong work ethic and attention to detail.
● Ability to work as part of a team
Preferred: Candidates with backgrounds in molecular biology, deep mutational scanning, proteomics or functional genomics
This position is open to international applicants as well as citizens and permanent residents of the United States and Canada. We can sponsor individuals for a J-1 visa, if required.
Postdoctoral Scholars are represented by UAW 4121 and are subject to the collective bargaining agreement, unless agreed exclusion criteria apply. For more information, please visit the University of Washington Labor Relations website (https://hr.uw.edu/labor/2019/06/03/agreement-reached-with-uaw-postdoctoral-scholars-on-2019-2021-contract)
Applications are accepted throughout 2020.
Applicants should apply electronically via Interfolio and submit the following:
1) Brief statement of interest
2) curriculum vitae
3) contact details for three references
University of Washington is an affirmative action and equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, creed, religion, national origin, sex, sexual orientation, marital status, pregnancy, genetic information, gender identity or expression, age, disability, or protected veteran status.
Founded in 1861, the University of Washington is one of the oldest public institutions in the west coast and one of the preeminent research universities in the world. The University of Washington is a multi-campus university comprised of three different campuses: Seattle, Tacoma, and Bothell. The Seattle campus is made up of sixteen schools and colleges that serve students ranging from an undergraduate level to a doctoral level. The university is home to world-class libraries, arts, music, drama, and sports, as well as the highest quality medical care in Washington State and a world-class academic medical center. The teaching and research of the University’s many professional schools provide undergraduate and graduate students the education necessary toward achieving an excellence that will serve the state, the region, and the nation. As part of a large and diverse community, the University of Washington serves more students than any other institution in the Northwest.