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A highly motivated post-doctoral research fellow is sought to carry out a research project in the lab of Dr. A. McGarry Houghton at Fred Hutchinson Cancer Research Center in Seattle, WA.
About the Lab
Lung cancer is the leading cause of cancer deaths worldwide, accounting for ~160,000 lives each year in the US alone. The Houghton Labs current research program focus is to comprehensively study the host immune response to non-small cell lung cancer (NSCLC). The lab also studies the role of myeloid lineage cells within the lung tumor microenvironment. Studies in this area are centered upon the mechanisms by which neutrophil lineage cells antagonize lymphocyte functions within the tumor microenvironment.
The Post-Doctoral Fellow will contribute to the Labs research agenda with a focus on the role of neutrophil subtypes in lung cancer. The fellow will conduct independent and collaborative research resulting in presentations and publications.
The techniques involved will include working with mouse models of lung cancer (Kras/p53, Pten/Lkb1, LLC syngeneic models, etc.) and carefully studying the immune response to the tumor using flow cytometry, multiplexed-immunohistochemistry, gene expression analyses (qPCR), protein assessment (ELISA) and others. Manipulation of these model systems with immune-based and other oncology drugs are commonplace in the lab. These in vivo studies will be supplemented by in vitro studies involving multicellular culture system, assays of cellular chemotaxis, function and viability and other standard protocols. The ability to analyze the complex datasets resulting from the above experimentation is essential.
To be considered, candidates must have:
A recent PhD, MD/PhD, or MD in a relevant biological field
Candidate is expected to have project leadership experience in a team environment, and must be able to work independently with little supervision.
Excellent written and verbal communications skills are essential.
A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and anti-racism in your career or that will be made through your work at Fred Hutch is requested of all finalists.
Our Commitment to Diversity
We are proud to be an Equal Employment Opportunity (EEO) and Vietnam Era Veterans Readjustment Assistance Act (VEVRAA) Employer. We are committed to cultivating a workplace in which diverse perspectives and experiences are welcomed and respected. We do not discriminate on the basis of race, color, religion, creed, ancestry, national origin, sex, age, disability (physical or mental), marital or veteran status, genetic information, sexual orientation, gender identity, political ideology, or membership in any other legally protected class. We are an Affirmative Action employer. We encourage individuals with diverse backgrounds to apply and desire priority referrals of protected veterans. If due to a disability you need assistance/and or a reasonable accommodation during the application or recruiting process, please send a request to our Employee Services Center at firstname.lastname@example.org or by calling 206-667-4700.
At Fred Hutchinson Cancer Research Center, teams of world-renowned scientists and humanitarians work together to prevent, diagnose and treat cancer, HIV/AIDS and other diseases. Researchers are discovering new ways to detect cancers earlier, improve treatments, and learn how to prevent cancers from growing. Although Fred Hutchinson opened its doors in 1975, its history began about 20 years before that. In 1962 Fred Hutchinson envisioned a center devoted to studying cancer, a disease that took his brother’s life. Today Fred Hutchinson is contributing to the next waves of breakthrough treatments and prevention strategies. Fred Hutchinson collaborates with the Seattle Cancer Alliance, the National Cancer Institute, and the University of Washington.