The Tufts University School of Dental Medicine's Department of Diagnostic Sciences invite applications for a Postdoctoral Fellowship in Gene editing and Tissue engineering. This post-doctoral fellowship is an opportunity to work on a project in the laboratory of Dr. Jonathan Garlick lab in collaboration with a cutting-edge startup company. Their goal is to use gene editing and tissue engineering to create immuno-privileged tissues. This postdoc will be responsible for leading development and working with technicians in the lab to create and culture CRISPR/Cas9 edited porcine and human cells for the creation of 3D human equivalent tissues.
This is a one-year appointment, and may be extended to 2-years, contingent on the meeting of milestones and sponsor funding.
Lead development of CRISPR/Cas9 edited porcine and human cells
Work with lab and startup company to develop experimental roadmap
Culture human and porcine cells, and engineer 3D tissues
Perform and analyze sequencing to verify CRISPR edits
Work with technicians to run histological analysis of tissues
Research and advise on innovations in fields related to model development
Present data to lab and company
Participate in general lab upkeep
Completion of a PhD in molecular biology or similar field
Strong background in CRISPR/Cas9-mediated genome editing, including gene design and construction, editing efficiency characterization, clonal selection, verification of edits
Background in mammalian cell culture
Experience in running and analyzing DNA sequencing analyses
Experience in phenotypic analyses (IHC, Western Blot, ELISA, qRTPCR)
Ability to work independently, and to plan and execute complex long term research projects
Strong record of productivity, motivation, and adaptability
Ability to work collaboratively with excellent oral and written communication skills
Trainees must be citizens or a non-citizen national of the United States or have been lawfully admitted for permanent residence at the time of appointment.
Interested candidates should submit a curriculum vitae, cover letter, a list of three recommenders (name and contact information), and a brief statement describing their background and research training via https://apply.interfolio.com/63346
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Internal Number: 63346
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