Research - Laboratory/Non-Laboratory, Staff/Administrative
Genome Editor (9612C) - 18259
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Application Review Date
The First Review Date for this job is: May 24, 2021
The IGI is composed of diverse researchers at the University of California, Berkeley and the University of California, San Francisco. Together, our scientists have powerful combined expertise. They conduct world-class research, driven by the real possibility to use genome engineering to treat human diseases and end hunger.
In addition to our scientific efforts, the IGI is committed to advancing public understanding of genome engineering, providing resources for the broader community, and guiding the ethical use of these technologies.
The Staff Research Associate will, under supervision, contribute to the design, execution, and analysis of experiments. This individual will be a key contributor to a research project focused on identifying new conditions for genome editing of specific cell types, with a focus on enabling accessible therapeutic use of this technology. This position will focus on testing the efficiency of various reagents and conditions in enabling genome editing in mammalian cells in tissue culture. Novel reagent formulations generated by the Wilson lab will be assessed in high-throughput assays performed by the employee. The employee will also make limited contributions to reagent preparation and quality assurance. Although the employee will not be responsible for designing the overall research plan, it is imperative that the employee is capable of skillfully adapting to constantly-evolving applications of the techniques used.
Perform high-throughput genome editing assays in tissue culture. These assays may utilize primary cells, human cell lines, or other mammalian cells. Responsibilities include planning practical details of experiments (including calculating reagent dilutions, scheduling of instrumentation, and ensuring that necessary supplies are adequately stocked).
Perform data processing and limited analysis of high-throughput genome editing assays performed in tissue culture. This involves quality control checks (verification that positive and negative controls worked) and establishing correlations between effective editing conditions and the reagents or formulations responsible.
Use lab computers and software to record and compile data; prepare results for presentation.
Basic life-sciences laboratory skills.
Using a pipettor, preparing solutions, diluting reagents, following an established protocol
Working knowledge of MS Office suite (Word, Excel, Powerpoint)
Detail-oriented and well-organized in terms of record-keeping, planning ahead, meeting deadlines
B.S. in a relevant field and/or equivalent experience/training.
Previous experience in a life-sciences laboratory setting.
Experience with CRISPR-Cas mediated genome editing
Experience with DNA analysis (PCR, Sanger sequencing, next-generation sequencing, etc.)
Experience with 96-well format high-throughput assays
Experience with mammalian tissue culture
Experience with nucleic acid extraction/purification
Experience with RNA/protein biochemistry
Experience with chemical biology and/or protein conjugation
Salary & Benefits
This is an exempt, monthly paid position. Annual salary is commensurate with experience.
For information on the comprehensive benefits package offered by the University visit:
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