Northern California HERC

Job Description

Cedars-Sinai is committed to pushing the frontiers of medicine and discovering new technologies and innovations that will change how we diagnose and treat disease. As an international leader in biomedical research, we translate discoveries into successful treatments with global impact. With your help, we can change the future of healthcare!

Are you ready to be a part of breakthrough research?

The Gibb Laboratory investigates inflammatory mechanisms in patients with sickle cell disease (SCD) and lupus, focusing on mechanisms regulating immune responses to red blood cell (RBC) antigens (i.e., KEL antigens) following RBC transfusion. The goal of these studies is to understand why patients with SCD and autoimmunity have the highest incidence of these detrimental anti-RBC antibody responses, which cause potentially fatal hemolytic transfusion reactions and severely limit access to compatible blood for these populations. Specifically, the lab has uncovered a critical role for antiviral cytokines (type I interferons, IFN?/?) and IFN?/?-stimulated genes (ISGs) in these antibody responses. Disrupting this pathway prior to RBC transfusion may promote transfusion safety by preventing hemolytic transfusion reactions. Learn more at Gibb Lab at Cedars-Sinai.

Working under direct supervision, the Research Associate I will perform a variety of routine experimental protocols and procedures to support the objectives of one or more laboratory research projects in a specific area of research. Assists in general laboratory activities, including maintenance of reagents and stocking of supplies. Files and monitors documents. The RA I will be able to perform routine cellular, micro-and molecular biology procedures including, but not limited to Western, Northern blot, DNA/RNA, PCR, protein extraction, cell culture, Immunohistochemistry, and staining. This position does not have supervisory responsibilities.

Primary Job Duties and Responsibilities:

• Keeps accurate and detailed project records of experiments and results.
• May assist with animal husbandry.
• Maintains lab equipment and related records.
• Transports, processes and logs samples.
• Maintains computer database with relevant clinical information.
• Performs lab maintenance duties, including glassware cleaning and sterilization.
• Maintains stocks of general lab materials, and places orders for lab equipment and supplies in a timely manner.
• Assists new students and fellows at the laboratory.
• Assists in the operation of specialized equipment and machinery.
• Observes and complies with safety standards and procedures.
   

Qualifications

Education:

• Minimum of a Bachelor's Degree in a science-related field.

Experience and Skills:

• No experience is required. Understanding of general research objectives.
• Knowledge of routine laboratory procedures, experimental protocols, and overall lab organization.
• Working knowledge of database management, personal computers, and presentation and imaging software.
• Must possess computer skills to include, but not limited to, Excel and Word.
• Excellent written and oral communication skills are essential.
• Function efficiently and cooperatively with a team of faculty, research associates, technicians, and students.
• Scheduling flexibility and timeliness including evening, weekend, and holiday rotation commitments. Travel may be required.

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About Cedars-Sinai Medical Center

Providing healthcare for more than 100 years, Cedars-Sinai has evolved into one of the most dynamic and highly renowned medical centers in the world. Along with caring for patients, Cedars-Sinai is a hub for biomedical research and a training center for future physicians and other healthcare professionals. This attracts exceptional talent to Cedars-Sinai, including world-renowned physician-scientists who seek a place where they can both conduct research and see patients--the ideal formula for discovery and its translation into cures. Our patients benefit from access to doctors at the top of their fields, and our researchers have an ideal community in which to study the impact of healthcare challenges, and reflect that knowledge in their research. The greater Los Angeles area in which Cedars-Sinai resides possesses unparalleled cultural and ethnic diversity which offers outstanding opportunities for translational and clinical research and a dynamic environment for medical education.Although community based, Cedars-Sinai is a major teaching hospital affiliated with the David Geffen School of Medicine at the University of California, Los Angeles (UCLA). Cedars-Sinai has highly competi...tive graduate medical education programs in more than 50 specialty and subspecialty areas, a graduate program in biomedical sciences and translational medicine, a clinical scholars program directed towards junior physicians with aspirations to become clinical scientists, and post graduate training opportunities.There are more than 250 full-time faculty members at Cedars-Sinai. The voluntary medical staff, comprised of more than 2,200 specialty board-certified or board-qualified physicians, represent all of the specialties and subspecialties and collaborate with full-time medical staff in the teaching responsibilities of the graduate medical education programs.

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